Cannabotech, an Israeli biomedical company, which has been developing a botanical drug based on cannabinoids extracts and Cyathus striatus fungal extract from the cannabis plant, has recently reported that during an experiment in a cell model in April 2022, the combination of fungus-cannabinoids killed pancreatic cancer cells with up to 100% efficacy.
This experiment proves that at low concentrations the combined treatment of the two witnesses much better anti-cancerous efficacy than any other effective ingredients individually (an effect known as synergy).
This result strengthens the assumptions about the combined treatment by cannabinoids and fungal extract that would efficiently treat pancreatic cancer with fewer side effects.
Under this experiment, the effect of cannabinoids and fungal extracts was examined on 3 subtypes of pancreatic cancer, of which the best results were seen in a subtype demonstrating Poorly Differentiated Cancer, considered the most common and violent in the population.
Another element assessed in these experiments was recognizing the extermination mechanism of cancerous cells.
The experiment shows that destroying these cancerous cells by the fungus is supported by increased cellular mortality known as apoptosis. However, the cannabinoid mechanism in destroying the cells is different.
This is a positive thing as the experiment displays that other mechanisms trying to kill cancerous cells hold a superior capacity for synergy between them.
Cannabotech’s pharmacological consultant, Dr. Yitzhak Angel, said that developing botanical medicine is a challenging process, and the results the firm has achieved represent a definite lead to believe these extracts are efficient and safe for using an anti-cancer treatment for pancreatic cancer.
The firm still says there is a long way to go in establishing this clinical viability, but it hopes it could bring some good reports to patients and develop a real solution to one of the most hazardous cancers.
Source Credit – https://www.prnewswire.co.uk/news-releases/promising-breakthrough-in-cannabotech-s-pancreatic-cancer-drug-for-the-first-time-ever-the-botanical-drug-has-shown-a-combined-anti-cancer-effect-between-cannabis-and-mushroom-804143745.html